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Season 2

# Title Orignal Air Date
01. Raindrops Keep Falling On My Head Sunday September 25th, 2005
As Meredith and Cristina discuss their relationship woes at the Emerald City Bar, their session of lamenting is interrupted when Joe, the bartender, collapses. And as Chief Webber recovers from brain surgery, he appoints one surgeon as interim chief - much to the dismay of another surgeon — and he assigns George to report back with hospital gossip. While a devastated Meredith learns more about Derek and Addison’s relationship, a confused Cristina tries to make decisions about her connection with Dr. Burke.
02. Enough Is Enough (No More Tears) Sunday October 2nd, 2005
When a family arrives at Seattle Grace Hospital after a serious car accident, Alex learns that their injuries are only the beginning of their problems. Meanwhile, as Dr. Webber recovers from brain surgery, it seems that his wife (guest starring Loretta Devine as Mrs. Webber) has some concerns about the state of their marriage.
03. Make Me Lose Control Sunday October 9th, 2005
Some very deep secrets are made painfully public when Meredith’s mother, who suffers from Alzheimer’s disease, is brought to Seattle Grace for a surgical procedure. Meanwhile, some frightening news about Cristina’s health is brought out into the open.

Source: ABC

04. Deny, Deny, Deny Sunday October 16th, 2005
As Cristina tries to recover, she proves to be a very difficult patient, and a visit from her mother doesn’t improve her demeanor any. And Meredith’s mother, Dr. Ellis Grey, has the hospital staff running in circles. Jeremiah, a cystic fibrosis patient, could benefit from Dr. Addison Shepherd’s medical knowledge, but her involvement in his surgery could delay her highly anticipated departure from Seattle Grace Hospital, leaving Meredith and Derek’s relationship hanging in the balance.

Source: ABC

05. Bring the Pain Sunday October 23rd, 2005
Meredith and Dr. Shepherd have to use more than medicine when a young woman’s traditionalist, religious father forbids her to have a life-saving operation. Meanwhile, George and Alex are forced to perform surgery under less than ideal conditions in an attempt to save a patient’s life, and its decision time for Derek and the two women in his life.

Source: ABC

06. Into You Like a Train Sunday October 30th, 2005
As Meredith nervously awaits a final decision from Derek, her angst is interrupted when a train crash brings several seriously injured patients to the hospital, including Bonnie and Tom, a pair of passengers who’ve been impaled on a metal pole. And Addison Shepherd sees great potential in Izzie, who must decide whether her loyalty as Meredith’s friend outweighs professional gain.

Source: ABC

07. Something to Talk About Sunday November 6th, 2005
Cristina, Izzie and Meredith aggressively pursue the case of Shane, a male patient who seems to have a hysterical pregnancy, which fascinates them and the entire medical staff; and a sheltered young patient inspires Alex to better express his feelings for Izzie.

Source: ABC

08. Let It Be Sunday November 13th, 2005
Derek and Addison Shepherd’s professional relationship is challenged when their closest friends come to Seattle Grace seeking a radical, preemptive operation to avoid breast and ovarian cancer. Meanwhile, George can’t understand why a patient who fell five stories doesn’t seem happy to have survived; an elderly gentleman makes a difficult decision upon learning that his wife has only a few months to live; Cristina and Burke try to have a “normal” date, and Chief Webber is disappointed by Bailey’s fellowship decision — until he learns her reasons.

Source: ABC

09. Thanks for the Memories Sunday November 20th, 2005
The Thanksgiving holiday is more difficult for the interns and residents than any of them is willing to admit, as Izzie plans a big dinner at Meredith’s — but it remains to be seen who among the invited guests will actually show up. Meanwhile, George endures the O’Malley tradition of hunting turkeys with his less-than-sophisticated family, and Meredith treats a patient who’s been in a vegetative state for 16 years.

Source: ABC

10. Much Too Much Sunday November 27th, 2005
Meredith is mortified when her “one night stand” shows up at the hospital suffering from priapism and needing medical attention; a woman carrying quintuplets is overwhelmed by numerous medical issues as she navigates her high-risk pregnancy; and Alex’s shortcomings frustrate Izzie.

Source: ABC

11. Owner of a Lonely Heart Sunday December 4th, 2005
Cristina Yang has little sympathy for Constance Ferguson (special guest star Rosanna Arquette), a prison inmate who jeopardizes her health just to get out of solitary confinement. Meanwhile the interns all keep careful watch on the family of premature quintuplets with a variety of serious health challenges, Izzie’s anger at Alex reaches boiling point, and Dr. Addison Shepherd decides to teach Izzie a very painful lesson.

Source: ABC

12. Grandma Got Run Over By a Reindeer Sunday December 11th, 2005
A young boy needs a heart transplant but doesn’t seem to want it, and his treatment causes Burke and Yang to have philosophical differences. Meanwhile, when the interns rally to help Alex prepare to re-take his exam, Meredith has to remind Izzie of the true spirit of the Christmas holiday; and despite a reconciliation with his wife, Derek isn’t in a festive mood.

Source: ABC

13. Begin the Begin Sunday January 15th, 2006
Izzie seems to be getting over Alex when she shares an undeniable chemistry with Denny Duquette, a patient who’s awaiting a heart transplant, and George treats Bex, a young teen hermaphrodite.

Source: ABC

14. Tell Me Sweet Little Lies Sunday January 22nd, 2006
— The truth is in short supply as Meredith and Cristina lie to each other about the status of their relationships. George is given the unpleasant task of discharging an elderly patient who’s no longer sick, but refuses to leave the hospital; and Alex learns his fate after re-taking his medical exams.

Source: ABC

15. Break on Through Sunday January 29th, 2006
The nurses at Seattle Grace Hospital go on strike, leaving the doctors to fend for themselves; Meredith’s mistake in treating an elderly patient is brought to light by the patient’s friends (June Lockhart, Betty Garrett and Rae Allen) and Izzie treats a pregnant teen.

Source: ABC

16. It’s the End of the World Sunday February 5th, 2006
Meredith’s fears that she is in for a bad day are realized when a medical case arrives at Seattle Grace that threatens the lives of everyone in the O.R.

Source: ABC

17. It’s the End of the World, Part 2 Sunday February 12th, 2006
Despite the best efforts of the Seattle Grace staff, the code black situation escalates.

Source: ABC

18. Yesterday Sunday February 19th, 2006
Someone from Derek and Addison’s past arrives in Seattle and shakes things up. Meanwhile, Burke learns about Christina’s secret and, after a visit with her mother, Meredith looks into more of her family’s dirty laundry.

Source: ABC

19. What Have I Done to Deserve This? Sunday February 26th, 2006
Meredith and George suddenly find themselves at odds at work. Meanwhile Bailey, although technically still on maternity leave, finds herself treating Addison for an unusual feminine issue, and Alex finds himself oddly jealous when Izzie pays more attention to Denny.

Source: ABC

20. Band-Aid Covers the Bullet Hole Sunday March 12th, 2006
It becomes a bad day for Cristina when Bailey instructs her to take care of her baby. Meanwhile, Derek and Addison come to terms with their relationship, and Denny continues to be an obstacle in Alex’s getting closer to Izzie.

Source: ABC

21. Superstition Friday March 17th, 2006
When a series of deaths occur at Seattle Grace, the uncanny events bring out the doctors’ superstitious sides and make Izzie nervous about Denny’s surgery. Meanwhile, Derek and Addison discuss making a more permanent living arrangement, and Richard treats a very special, old friend.

Source: ABC

22. Name of the Game Sunday April 2nd, 2006
George begins to overstay his welcome at Burke’s apartment; Meredith learns a secret about her father; Bailey worries her colleagues will not treat her the same now that she’s a mother; and Alex gets a lesson in bedside manners.

Source: ABC

23. Blues for Sister Someone Sunday April 30th, 2006
Izzie grills George about the personal details of his life, Addison takes Alex to task about a sensitive case, and Burke feels the pressure when he treats his musical hero.

Source: ABC

24. Damage Case Sunday May 7th, 2006
The interns deal with a family involved in a car accident, Derek lets his emotions get the best of him, and Burke and Izzie make a new suggestion to Denny.

Source: ABC

25. 17 Seconds Sunday May 14th, 2006
17 Seconds Finn gives a health update on Doc, Meredith is assigned to work with Callie for the day while George gets paired with Derek, and Burke and Izzie continue to try to find a heart for Denny.

Source: ABC

26. Deterioration of the Fight Monday May 15th, 2006
Izzie and George attend to Denny as the pressure increases to find him a new heart, Cristina suddenly finds herself in charge of an ER, and Derek grapples with the realization that the life of a friend is in his hands.

Source: ABC

27. Losing My Religion Monday May 15th, 2006
Richard goes into interrogation mode about a patients condition, Callie confronts George about his feelings for her, and Meredith and Derek meet about Doc.

Source: ABC

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